Misplaced protein causes heart failure

Decreasing the density of microtubules inside heart muscle cells prevents the abnormal localization of a critical protein called junctophilin 2 (JP2), and protects mice from heart failure, new research has found. Conversely, increasing microtubule density causes abnormal localization of JP2, which leads to loss of normal heart cell function and ultimately heart failure.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/nm_zGOQq12c/140306103935.htm

    

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